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Infusion of residual DMSO instantly cryopreservation and thawing can cause dosedependent cryoprotectantrelated toxicity. Adverse reactions of this particular infusion of cryopreserved HSC have been widely described in HSC graft recipients.1,2,3,4 Reported conditions range from mild (a sick stomach, nausea) To severe (Acute renal failure and cardiac or lung arrest). Most common toxicities associated with the infusion of cryopreserved HSC grafts include nausea, throwing up, stubborn abdominal pain and chills,3,5,6,7 a range of symptoms who are not totally abrogated with premedication.
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